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Codeine Cough syrup, sometimes referred to as Purple Drank or Sizzurp, is a mixture traditionally made with prescription cough syrup containing codeine and promethazine. When combined with a flavored soda or candy, it creates a sweet but powerful beverage.

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The drug is used in curring some allergic diseases and reactions such as rash, itching, eczema, drug rash, serum sickness, Quincke’s edema, hay fever, anaphylactic shock, bronchial obstructive syndrome (as part of complex therapy). Codeine-Lean
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PROMETHAZINE | Side Effects of Promethazine

Like most medications, Promethazine can also cause side effects. Some are mild, while others may require medical attention. These are the side effects listed below;

The most frequent effect, especially when starting treatment is Drowsiness and dizziness

It leads to temporary vision issues may occur

Constipation is one of the effect and reduced digestive movement due to sedation.

It causes difficulty in breathing or slow breathing which is especially dangerous when mixed with depressants like alcohol or opioids.

It thus causes confusion, hallucinations, or disorientation and it is possible in elderly patients or with high doses.

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Because of its strong sedative effects, Promethazine must be used responsibly. The safety considerations include:

Always try to avoid combining prom with alcohol, opioids, or other sedatives.

It is not recommended for children under 2 years old due to risk of respiratory depression.

Pregnant or breastfeeding women should consult a doctor before use.

Patients with liver disease, breathing problems, or glaucoma should use with caution.